Original access to 5-aryluracils from 5-iodo-2′-deoxyuridine via a microwave assisted Suzuki-Miyaura cross-coupling/deglycosylation sequence in pure water - Université de technologie de Compiègne Accéder directement au contenu
Article Dans Une Revue RSC Advances Année : 2014

Original access to 5-aryluracils from 5-iodo-2′-deoxyuridine via a microwave assisted Suzuki-Miyaura cross-coupling/deglycosylation sequence in pure water

Résumé

A facile and efficient methodology to obtain various 5-aryluracil derivatives was developed through a two steps sequence: a ligand-free Suzuki-Miyaura cross-coupling reaction starting from totally deprotected 5-iodo-(2′-deoxy)uridine followed by a very simple deglycosylation procedure in pure water with assistance of microwave irradiation.

Domaines

Chimie
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Dates et versions

hal-04391323 , version 1 (12-01-2024)

Identifiants

Citer

T. Lussier, G. Hervé, G. Enderlin, Christophe Len. Original access to 5-aryluracils from 5-iodo-2′-deoxyuridine via a microwave assisted Suzuki-Miyaura cross-coupling/deglycosylation sequence in pure water. RSC Advances, 2014, 4 (86), pp.46218-46223. ⟨10.1039/c4ra04814h⟩. ⟨hal-04391323⟩
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