Abstract Today we live a high increasing digitalization in industry 4.0. As part of the evolution of CAD solutions on the market, there is a particular interest in new generation software which are distributed as Software-as-a- Service (SaaS) such as Onshape, 3D Experience, Fusion 360, etc. In order to prepare engineering students for integrating such software within the Université de Technologie de Compiègne (UTC), a further practicing study is carried out in this paper. This study aims to identify, analyze, experiment, evaluate and compare the capacities of Cloud-based CAD solutions on the market and in scientific research work in order to define potential benefits for their implementation in mechanical engineering education. Therefore, we tested two use scenarios of the two Cloud-based software; Onshape and Fusion 360 on a case study. Then, we discussed the comparison results.