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Université de Technologie de Compiègne |
Journal articles
Sesamol–based terpenoids as promising bio‐sourced crop protection compounds against the wheat pathogen Zymoseptoria tritici
Abstract : BACKGROUND
Research into environmentally friendly alternatives to conventional plant protection products, to promote sustainable agriculture and healthy food, is strongly encouraged.
RESULTS
In this context, 20 naturally occurring terpenoids and phenolic compounds were selected and evaluated in vitro as crop protection compounds against Zymoseptoria tritici, the causal agent of Septoria tritici blotch of wheat. After selection of the most active compounds, some hemisynthetic modifications were conducted to modify their lipophilicity. These modifications led to the discovery of sesamol esters as promising antifungal agents, with IC50 around 10 μg/mL and a total absence of cytotoxicity against human cells.
CONCLUSION
These sesamol-based derivatives should be selected for further evaluations in planta to validate their use as wheat crop protection agents. Moreover, the importance of a balanced hydrophily/lipophilicity ratio should be further studied.
https://hal.utc.fr/hal-03109904
Contributor : Antoine Fayeulle Connect in order to contact the contributor
Submitted on : Thursday, January 14, 2021 - 10:06:46 AM
Last modification on : Thursday, November 25, 2021 - 8:22:30 AM
Contributor : Antoine Fayeulle Connect in order to contact the contributor
Submitted on : Thursday, January 14, 2021 - 10:06:46 AM
Last modification on : Thursday, November 25, 2021 - 8:22:30 AM