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Journal Articles ACS Omega Year : 2019

Design of New Antifungal Dithiocarbamic Esters Having Bio-Based Acrylate Moiety

Abstract

Nine new dithiocarbamic esters derived from bio-based acrylic acid were synthesized and evaluated for their in vitro antifungal activity against the phytopathogenic fungus Fusarium solani and fungi-like oomycete Phytophthora infestans. Among these nine dithiocarbamic derivatives, compound 6 (tert-butyl 3-(N,N-diethyldithiocarbamoyl)-propanoate) showed interesting antifungal efficacy at low concentration compared to the other tested dithiocarbamates. The structure–antifungal activity relationship of these designed dithiocarbamic esters is discussed.

Dates and versions

hal-02190983 , version 1 (23-07-2019)

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Etienne Veignie, C. Ceballos, Christophe Len, Catherine Rafin. Design of New Antifungal Dithiocarbamic Esters Having Bio-Based Acrylate Moiety. ACS Omega, 2019, 4 (3), pp.4779-4784. ⟨10.1021/acsomega.8b03685⟩. ⟨hal-02190983⟩
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